Jing Liang 🇺🇦 @AppleHelix
Entrepreneur. Drug hunter. Anti-ideologues, Anti-medical nihilists, Optimist My NGO: https://t.co/yDWRnOYAyY https://t.co/SOf8c5OZm6 Joined December 2009-
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@Sanctuary_Bio @BiotechObserver WTH are we doing in XBI? :)
The problem is that you can't patent miR-302b. Too much in literature. But if you do a combinatorial optimization of miR-302b sequence to get better efficacy, then you have new IP
If I were to guess what NewLimit is doing, I think they are delivering exosomes with miRNA. A lot of literature on miR-302b. A biotech company in China is doing it
Following breakthrough results, we’re bringing longevity medicine to human trials. We’ve raised a $435M Series C led by @foundersfund to make it happen. Reprogramming cell age has the potential to create more healthy years for everyone. We're closer than ever to realizing it.
And a comprehensive screening by and testing of miRNA would probably be a pretty sexy platform
Let me elaborate on this more. If Life Science VCs can't get $1-3B exits, they will cease to exist. LPs need DPI,
Excited for us to lead NewLimit's $435M Series C Largest investment we've made into therapeutics in a long time But what we love about @jacobkimmel & team is that they're building a company for a mega-outcome rather than just the standard Boston biotech $1b - $3b outcome
Impressive results from a phase 3 trial of Iza-Bren (anti-HER3/EGFR TOPO1 ADC) vs chemo in pretreated mTNBC, with improvement in PFS and OS. High rate of hematologic toxicities, including 5% febrile neutropenia. Phase 3 ongoing to confirm these results in a global population.
Good point.
Prediction markets can never work in Biotech trial outcomes - $ABVX is a super clear example.
@BiotechObserver @JacobPlieth It is going to be a nail biter on the OS
@jryckman3 Though I don't agree with your point 2. SOC is the Darax control arm, what other treatment do you think drop outs can get?
It is funny that Vinay Prasad uses ICI to throw shade at daraxonrasib saying ICIs "are cures" Just 2 years ago, he published a paper saying ICIs are "modest": "ICIs are increasingly used in the treatment of cancer, yet the median OS improvement is modest, and many ICIs have not been tested for OS benefit." sciencedirect.com/science/articl…
The story telling is so different between life science VCs and tech VCs.
Excited for us to lead NewLimit's $435M Series C Largest investment we've made into therapeutics in a long time But what we love about @jacobkimmel & team is that they're building a company for a mega-outcome rather than just the standard Boston biotech $1b - $3b outcome
@jryckman3 Appreciate the thoughtful reply!
Prasad does like to throw shade. But there are some truths. 1. ICI —some amazing cures in end-stage pts; 2. median OS 13 mos not great; 3. Pancreatic control arm standard since 2015 (median OS 6 mos) = field stagnation Next steps. 1. First line 2. biomarker matched combos
It is funny that Vinay Prasad uses ICI to throw shade at daraxonrasib saying ICIs "are cures" Just 2 years ago, he published a paper saying ICIs are "modest": "ICIs are increasingly used in the treatment of cancer, yet the median OS improvement is modest, and many ICIs have
Perhaps the most important breast cancer discussion this year at ASCO. A brilliant analysis of PFS2 and its meaning (or lack thereof) in advanced breast cancer. Required viewing for all clinical investigators.
#ASCO26 PFS2 is a highly heterogeneous endpoint. From Meredith Regan’s excellent discussion on PFS2👇
Backup plan when that PhD doesn't work out
Interesting storyline for NHL Finals: Carolina Hurricanes GM Eric Tulsky has a PhD in Chemistry from Berkeley. Before joining them in 2014, he was offered a job with Apple to work on battery tech (but turned it down). Started in the analytics department and since hired
More relevant question is what will FDA do about this observation.
Legend Biotech shares first in vivo CAR-T data in lymphoma, its next act after Carvykti 6/12 overall response rate and 5/12 complete response BUT all responses happened at second dose level: 6/6 ORR and 5/6 CR ...so zero responses at first DL endpoints.news/legend-biotech…
Okay sounds like you agree with all of his points: 1) It is not a cure [No one said it was! But it is an amazing breakthrough given how many attempts failed!] 2) Drop out due to declined treatment. So what, they are censored afterwards. Q for YOU: If Darax arm had higher dropout, would you then think the data is better? 3) OS > PFS. VP had some convoluted speculation which was nonsense. He has always criticized drugs where PFS > OS. Q for YOU: If PFS was > OS, you would then think the data is better? 4) Stupid argument about giving Darax to frail people. Chemo is easy peasy for frail patients?
Bertrand Delsuc @BertrandBio
19K Followers 234 Following Views=mine only, RT-like=/=endorse, no advice. 16y in Tech (chip design) & 10y following bios. Preplanned pause.
Bruce Booth @LifeSciVC
56K Followers 736 Following Early stage biotech VC. Recovering scientist. Opinions expressed are solely my own and do not express the views or opinions of Atlas Venture.
Jacob Plieth @JacobPlieth
33K Followers 285 Following Journalist @ApexOnco. The Wolverine Of Biotech / Mr ASH. Never paid for a blue tick. Interested in: oncology. Not interested in: what stock you bought today.
Sports_Bios @Sports_bios
14K Followers 87 Following
Professor Oak @Prof_Oak_
14K Followers 765 Following Biopharma Musings | Genetic Medicine & Rare Disease | Buyside Turned Operator | Not Investment Advice | DYODD
Peter Kolchinsky @PeterKolchinsky
64K Followers 183 Following Managing Partner, RA Capital Management. We build & invest in biotech companies. Scientist. Author, The Great American Drug Deal. https://t.co/ARVLrrTQU4
avidresearch @avidresearch
12K Followers 1K Following
Daphne Zohar @daphnezohar
27K Followers 796 Following Founder, Board & CEO of @SeaportTX. Co-founder Karuna Tx (now at BMS). previously Founder, Board & CEO PureTech. Cofounder/host @BiotechCH.
DRUGS @drug_smolecules
9K Followers 564 Following ☣Femtomolar potency poems and limericks ☣Oceanic Boundlessness (p=0.0001)
Michael Gilman @michael_gilman
25K Followers 766 Following Scientist, entrepreneur, ex-biopharm exec, former FM radio jock, lifelong hockey fan, aspiring guitar player, #immigrant. CEO @ArrakisTx. Just @gilman on...
Matthew Herper @matthewherper
111K Followers 3K Following Writing and events at STAT. This is biology's century; Every data point has a face. ‘21 Polk Award. Signal: MattHerper.92
Andrew Pannu @andrewpannu
15K Followers 296 Following daily dose of biotech & healthcare commentary • founder @sleuthinsights • building software for the bioeconomy
Andy Biotech @AndyBiotech
75K Followers 724 Following #Biotech Investor | Recovering Scientist | May have L/S position in names mentioned | Opinions are strictly my own and not intended as investment advice
Goose Data (wa/wa) @GooseData
6K Followers 215 Following Biotech visionary. Looking for best drugs with goose data. Retweets mean honking endorsement.
dough @semodough
43K Followers 633 Following BIOTECH man LONGTERM FOCUS many positions-also trade around my CORE holdings my opinion only do your own research with me
Peter Suzman @Biomaven
9K Followers 3K Following Long-time small-cap biotech investor & entrepreneur - currently co-founder of biotech startup. Perennial loser in New Yorker caption contest.
Mo @mopunjwani
1K Followers 4K Following Partner @seedtosunflower; alum Mural Health, @generalcatalyst, @bostoncollege 🦅🚴🏽🧗♂️
Connor Anderson @ConnorAndrsn
199 Followers 342 Following PhD @ucalgary @HotchkissBrain • Building Bio in Alberta • Baseball addict ⚾️ (he/him)
Scofiled @Scofiled0369
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Francesco @0xfrankly
60 Followers 951 Following PhD student in AI for medical image analysis @SanRaffaeleMI @myunisr 🫀👨🏻💻
Mandy Davis Aitken @davisa20
1K Followers 3K Following Vice President, Meetings Services @ASCO, political junkie, avid reader, and Capitol Hill resident. Views are my own. Find me at https://t.co/JGPbrqYNG2
Inside Matters Podcas... @_insidematters
87 Followers 131 Following The gut health podcast, hosted by @drjamesmcilroy. In-depth discussions about how our gut microbiome impacts our health, well-being, mood and much more.
CX Liu @cxliu06
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doogoadlksj @NYCorBust
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Brian Bodemann @BTC_Biotech_guy
116 Followers 182 Following 12 years in Bitcoin, 20 years in Biomedical Research & Business Development, Ph.D. Pharmacology
Mars Liber @Mars_Liber
0 Followers 75 Following Molecular biology undergraduate | Interested in gene editing, CRISPR & RNA biology
Mohammad Jaffery @mjafferyy
42 Followers 438 Following Immune memory @RushMedical @UChicagoMed @CWRU
ondaclock16 @DouglasSu293416
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vidyut @vidyut1100
122 Followers 3K Following
Jędrzej @microcurt
21 Followers 179 Following MD zainteresowany metodologią i statystyką biomedyczną. Rezydent hematologii
SR @PatternNotes
200 Followers 782 Following 🧩Educational discussion of historical market structure & liquidity. No buy/sell/hold recommendations. Liquidity ≠ prediction. Not signals. Not financial advice
🐊ZK For Tre🐊 @ZKForTre
3K Followers 1K Following UF MD/PhD. PhD Neuroscience. Neurobio/Neuroimmuno/Metabolism/Stress Biology. Artist formerly known as Dr. Love/Pre-Med Guy. 🤟.
Ibrahim Azar, MD @IbrahimAzarOnc
23 Followers 188 Following Medical Oncologist. Interest in thoracic & GI malignancies. @ASCOTECAG and @themednet GI med onc editor. Currently @IHACares Alum @mcgillu @karmanoscancer AOA
Greg Burrell, MD @gregburrellmd
479 Followers 1K Following Chief Medical Officer at Gravie (https://t.co/KsViegctAM), Co-Founder @carbonhealth, prev Associate Prof of Medicine at UCSF
Santhosh Ambika @RenoHemonc
4K Followers 4K Following Oncologist/Hematologist- Doing my part to help onc patients. + fintwit
Klotzkette @Klotzkette
2K Followers 7K Following Tom Braegelmann. No legal advice. Attorney Advertizing. Prior results do not guarantee a similar outcome. Imprint/Impressum: https://t.co/92TXZIzPkR
Dr G. @hemeoncmd
222 Followers 1K Following Over 2 decades in practice ad a Hematologist/Oncologist. Clinical Researcher - AdventHealth Colorado
J @joseluisrs2795
664 Followers 322 Following
Vincent Nguyen @vinnywinny313
6 Followers 89 Following Princeton ‘25. I had been lurking on here for too long so here is this account.
Erik Zapata Pinillos @erzapi
221 Followers 917 Following Emmancipate yourselves from mental slavery.
Ankit kansagra @kansagraMD
1K Followers 1K Following MM doc | @tghcares @usouthflorida I Lead expansion, integration and growth at TGH so more patients get access to advanced care | Opinions are mine
Ani Trghwi @logicrxt
102 Followers 4K Following
Sasha and immunology @immune_goeswild
20 Followers 159 Following kinda zoomer biotech, but with good vibes
Calvin Lai @calvinlaibio
3 Followers 58 Following
James Bayne @JamesBa95200124
84 Followers 79 Following Co-Founder Nucleate UK / Computational biology DPhil at Oxford & The Crick
David Ruhl @David_A_Ruhl
81 Followers 584 Following Neuroscientist and writer in San Diego, CA. I play in the ocean a lot but don't tweet about it.
Joanne Peng @JoanneZPeng
3K Followers 1K Following neuroai & biotech | research director https://t.co/eEL2wWrPDA | @mit @princeton @thielfellowship | 🇨🇦
Jason Romero @rasonjomero04
59 Followers 2K Following Husband, father, and cancer immunotherapy RnD professional. Views are my own and don’t represent the company I work for.
uNknown @uNknown_trader1
82 Followers 495 Following Macro & Technicals Analysis Investor & Daytrader All comments and posts are for educational and entertainment purposes only.
Scott Beeler @Scott_Beeler
181 Followers 233 Following Heme-Onc Fellow @WashUHemOncFell | physician-scientist @KellyLBolton lab | myeloid neoplasms & clonal hematopoiesis | opinions my own
Denise Louis 🌻 @birdyluisa
1K Followers 6K Following From cornfields of Illinois➡️Chicago➡️ Europe➡️Asia. Paying attention but mostly reading and exploring nature btw Appalachians and Atlantic.
Ayman Sayyed @AymanAbualhassa
275 Followers 3K Following Allogeneic Stem Cells Transplantation Fellow, Princess Margaret Cancer Centre
Louis Krasenics @LKrasenics
8 Followers 76 Following
Mads Karkov @KarkovMads
43 Followers 515 Following
Peter Törngren @peter_torngren
719 Followers 3K Following Gillar börs, index, analyser. Tweets är inte råd utan endast jag som ventilerar mina privata tankar. Fil kand i Systemvetenskap och Ek kand i Företagsekonomi.
Brad Loncar @bradloncar
82K Followers 367 Following #Biotech, Founder of @BiotechTV, KC native, @univmiami hurricane.🧬🙌
Adam Feuerstein ✡�... @adamfeuerstein
127K Followers 798 Following Biotech reporter @statnews. Dog ❤️er. Polk Award winner. #COYS. Said one analyst: The likes of Adam Feuerstein attack viciously. On Signal: stataf.54
Bertrand Delsuc @BertrandBio
19K Followers 234 Following Views=mine only, RT-like=/=endorse, no advice. 16y in Tech (chip design) & 10y following bios. Preplanned pause.
Bruce Booth @LifeSciVC
56K Followers 736 Following Early stage biotech VC. Recovering scientist. Opinions expressed are solely my own and do not express the views or opinions of Atlas Venture.
Jacob Plieth @JacobPlieth
33K Followers 285 Following Journalist @ApexOnco. The Wolverine Of Biotech / Mr ASH. Never paid for a blue tick. Interested in: oncology. Not interested in: what stock you bought today.
Sports_Bios @Sports_bios
14K Followers 87 Following
Professor Oak @Prof_Oak_
14K Followers 765 Following Biopharma Musings | Genetic Medicine & Rare Disease | Buyside Turned Operator | Not Investment Advice | DYODD
Peter Kolchinsky @PeterKolchinsky
64K Followers 183 Following Managing Partner, RA Capital Management. We build & invest in biotech companies. Scientist. Author, The Great American Drug Deal. https://t.co/ARVLrrTQU4
Elmo @BiotechElmo
5K Followers 336 Following
avidresearch @avidresearch
12K Followers 1K Following
Daphne Zohar @daphnezohar
27K Followers 796 Following Founder, Board & CEO of @SeaportTX. Co-founder Karuna Tx (now at BMS). previously Founder, Board & CEO PureTech. Cofounder/host @BiotechCH.
DRUGS @drug_smolecules
9K Followers 564 Following ☣Femtomolar potency poems and limericks ☣Oceanic Boundlessness (p=0.0001)
Michael Gilman @michael_gilman
25K Followers 766 Following Scientist, entrepreneur, ex-biopharm exec, former FM radio jock, lifelong hockey fan, aspiring guitar player, #immigrant. CEO @ArrakisTx. Just @gilman on...
Matthew Herper @matthewherper
111K Followers 3K Following Writing and events at STAT. This is biology's century; Every data point has a face. ‘21 Polk Award. Signal: MattHerper.92
Andrew Pannu @andrewpannu
15K Followers 296 Following daily dose of biotech & healthcare commentary • founder @sleuthinsights • building software for the bioeconomy
Bio Stocks™ @BioStocks
72K Followers 93 Following Investor/trader focused primarily in the biopharma sector. Tweets are not investment advice and are not recommendations of any kind.
Andy Biotech @AndyBiotech
75K Followers 724 Following #Biotech Investor | Recovering Scientist | May have L/S position in names mentioned | Opinions are strictly my own and not intended as investment advice
Antoni Chan MD (Prof) @synovialjoints
4K Followers 2K Following MD PhD Consultant Rheumatologist & Lead Physician, Professor @UniofReading Gold Changemaker NASS, Digital Health, Executive Coach and Appraiser
Dr.Steven R. Feldman @DrSteveFeldman
1K Followers 335 Following Dermatologist, scientist, journal editor, museum curator, & above all, optimistic about other people.
@derm_ce @derm_ce
245 Followers 5 Following Your only source for CE/CME-accredited, serialized tweetorials in dermatology!
Fugitive42 @fugitive4242
45 Followers 13 Following
Nous Research @NousResearch
202K Followers 25 Following World-class open source AI https://t.co/vrD0aDJeto
emozilla @theemozilla
12K Followers 1K Following catholic, ai researcher, co-founder/cto of @NousResearch alignment: whatever the opposite of yudkowsky + bryan johnson is. blessed be God in all his designs.
AI Finance Labs @aifinancelabs
9K Followers 3 Following $200M+ invested alongside Grok, Chat, DeepSeek & Claude on @joinautopilot Designed @theaiportfolios @grkportfolio by @alejandroll10
Keith Dredge @KeithDredge
223 Followers 175 Following Drug Development Professional committed to translating science into tomorrow's medicine. Opinions are mine. 🇮🇪🇦🇺
Jeremy Blitzer @JeremyBlitzer
42 Followers 427 Following Stanford MD/PhD and biotech builder tackling aging + metabolism. Global macro junkie.
Steve Derby @GeneralVentures
279 Followers 434 Following Father of two boys. Founder of venture/hedge funds. Current investing activities focused on helping life sci, tech, and energy entrepreneurs. Not inv. advice
Tejas Patil @TejasPatilMD
1K Followers 403 Following Thoracic oncologist @CUCancerCenter, via @Penn & @KeckMedUSC | Interests in #biomarkers & #PrecisionOncology in #lungcancer | Classical pianist on the side
Eileen M O’Reilly @EileenMOReilly
7K Followers 3K Following Oncologist MSK. TCD alum. Interests Pancreas, genomics, Hepatobiliary, GI Cancers, IRB Chair, Editor, Drug Development, Clinical trials, Alliance GI, NCTN
just a random dude @jy201506
477 Followers 70 Following a scientist who also knows a bit of finance | views expressed are my own, based on public information. not medical or investment advice.
priya joseph @ayirpelle
5K Followers 7K Following geek, entrepreneur, 'I strictly color outside the lines!', opinions r my own indeed. @ayirpelle , universal handle at this time
not sure @myberkeley3
63 Followers 52 Following
Dr. Antonio Calles �... @Tony_Calles
12K Followers 4K Following Medical Oncology 🏥 Hospital General Universitario Gregorio Marañón ⎪@myESMO Faculty 🫁 ⎪#endlungcancer #lcsm
Keiran Smalley @LabSmalley
1K Followers 1K Following Director of the skin cancer research center at Moffitt. Interested in melanoma: cutaneous, acral, pediatric and uveal. #melanoma #uveal #pediatric 🇺🇦
Mario Balsa @MarioBalsaMD
2K Followers 688 Following Galleguiño 🌊 | Med Onc resident @ICO_oncologia | Skin cancer, IO & cell therapy 🎯 | 2025 Rotation Research @UTMDAnderson 🇺🇸 | @OncoAlert team💥 | Pianist 🎹
Han Seoul Ohno @han_seoul_ohno
973 Followers 194 Following World's worst computational biologist | 2026 Binaries Score Card: GRCE 0:1 CYTK 1:0
Isaac Saul @Ike_Saul
81K Followers 3K Following Founder @tanglenews. Pitt alum. Fighting partisan nonsense and politically independent. Speaking/Media inquiries: [email protected]
BioSignal @BioSignal
840 Followers 7 Following Concise biotech intelligence. Oncology, cell therapy, antibodies, ADCs, gene therapy, and early clinical signals. High signal, low noise.
Giampaolo Bianchini @BianchiniGP
3K Followers 353 Following Head Breast Cancer Group; Head translational and immunotherapy research group; San Raffaele Scientific Institute, Milan, Italy; #PrecisionImmunology
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6K Followers 1K Following Venture Capitalist, Entrepreneur, Husband, Father. @amplifypartners
GXL @gxl_ai
148 Followers 0 Following GXL is an applied research lab working at the intersection of artificial intelligence and biomedicine.
Lilian Weng @lilianweng
255K Followers 178 Following Co-founder of Thinking Machines Lab @thinkymachines; Ex-VP, AI Safety & robotics, applied research @OpenAI; Author of Lil'Log
Readwise @readwise
213K Followers 3K Following Save your best highlights from Kindle, Twitter, Pocket, Instapaper, iBooks, and 30+ others. Then revisit, search, organize, and export them seamlessly.
Daave “3 and 30” ... @institLPGP
5K Followers 577 Following investor at top-3 endowment. do not own the panthers. tyj.
Mr. T @MrTinvests
23K Followers 99 Following I post my actual positioning. Daily. 10+ yrs in markets. 25k to 100k challenge live.. ( at 40k ) Sharing my journey so you can avoid my mistakes
Irrational Analysis @insane_analyst
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Jonathan Laxton MD, F... @dr_jon_l
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Mohamed Derbala, MD @MDerbalaMD
402 Followers 273 Following Sr. Research Scientist, MD Anderson Cancer Center. Tweets are mine.
Pushkar Ranade @magicsilicon
10K Followers 2K Following Silicon technologist. I write about the evolution of the semiconductor industry in the next wave of computing.
Peter Ottsjö @peterottsjo
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