RewitzLab @LabRewitz
We use the model insect Drosophila melanogaster to study totes dope hormonal regulation of growth & development, as well as models of neuropsychatric disorders. rewitzlab.dk Copenhagen, Denmark Joined July 2019-
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This study was supported by @lundbeckfonden, @novonordiskfond, and @Carlsbergfondet — we are grateful for their support. 🙏
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New from our lab in eLife! 🧠 We uncover how gut inflammation signals to the brain through glial JAK–STAT signaling, revealing a cytokine pathway that links intestinal health to sleep. 👉 doi.org/10.7554/eLife.…
Why do we feel sleepy when sick, and how does gut health affect sleep? 🤒💤 Our new eLife study shows that gut inflammation signals to the brain to trigger sleep. 👉 doi.org/10.7554/eLife.… #Neuroscience #SleepResearch #GutBrainAxis
RewitzLab retweeted
Researchers have discovered a cell surface receptor that is essential for adipose #tissue responding properly to #insulin. When the receptor is inactivated, the response to insulin is insufficient. However, a researcher says that it may be possible to stimulate the receptor – thereby protecting against the #development of type 2 #diabetes. #sciencenewsdk sciencenews.dk/en/recently-di…
We are thrilled to share that @eLife has now published our "reviewed preprint" on how signaling from the gut to glia connects intestinal inflammation to sleep in #Drosophila! elifesciences.org/reviewed-prepr… @HalbergLab @Colombani_lab @lundbeckfonden @novonordiskfond @Carlsbergfondet
We are excited to share our recent work on gut-to-glia communication linking intestinal inflammation with sleep in #Drosophila! Many thanks to @HalbergLab and Andersen and @Colombani_lab! @lundbeckfonden @novonordiskfond @Carlsbergfondet @UCPH_Research biorxiv.org/content/10.110…
Thrilled to share our work! Thanks to @novonordiskfond and @DFF_raad, we unveil how LGR signaling mediates crosstalk between muscle, neuronal, and adipose tissues, protecting against #insulinresistance and offering insights into #Diabetes and #Obesity. nature.com/articles/s4146…
We are excited to share our recent work on gut-to-glia communication linking intestinal inflammation with sleep in #Drosophila! Many thanks to @HalbergLab and Andersen and @Colombani_lab! @lundbeckfonden @novonordiskfond @Carlsbergfondet @UCPH_Research biorxiv.org/content/10.110…
RewitzLab retweeted
Latest from the lab: What are the mechanism by which insects maintain systemic ion and water balance as they interact with their environment? Another great collaboration with @DenholmLab!annualreviews.org/eprint/FXMYNQH…
RewitzLab retweeted
Online now! Glycolysis-derived alanine from glia fuels neuronal mitochondria for memory in Drosophila dlvr.it/SyTZ2L
RewitzLab retweeted
Let's try this again - look's like twitter can't handle the video 😂. Really excited to share the lab's first Drosophila paper and it's a big one. Check out our preprint shorturl.at/gqrvO where we present the complete neural connectome of an animal circadian clock
RewitzLab retweeted
New paper: Petsakou, A., Liu, Y., Liu, Y. Comjean, A., Hu, Y. and Perrimon, N. Cholinergic neurons trigger epithelial Ca2+ currents to heal the gut. Nature (2023). doi.org/10.1038/s41586…
RewitzLab retweeted
Michael Ashburner (1942-2023). Rubin GM. Curr Biol. 2023 Aug 18:S0960-9822(23)01072-2. doi: 10.1016/j.cub.2023.08.029.
Our preprint on #Obesity-driven #InsulinResistance reveals a muscle-neuronal-fat axis adapting to high-sugar-induced obesity conditions by influencing insulin secretion & sensitivity in #Drosophila. @Halberglab biorxiv.org/content/10.110…
RewitzLab retweeted
Our last review: Drosophila TNF/TNFRs: At the crossroad between metabolism, immunity, and tissue homeostasis J. Colombani & D.S. Andersen - FEBS Letters - Wiley Online Library febs.onlinelibrary.wiley.com/doi/10.1002/18…
RewitzLab retweeted
Curious about how some beetles have evolved to drink, not with their mouths, but with their rectum? Check out our latest Quick Guide in the current issue of @CurrentBiology. In collaboration with @RobinBeaven @DenholmLab sciencedirect.com/science/articl…
RewitzLab retweeted
If you are interested in how genes are regulated in response to dietary sugar, please check out our recent publication 'Sugar-responsive inhibition of Myc-dependent ribosome biogenesis by Clockwork orange': cell.com/cell-reports/f… 1/
RewitzLab retweeted
Fresh preprint! Collaborative work with Chris Wegener's lab looking at the release of clock neuropeptide pigment dispersing factor.
PDF neuropeptide signals independently of Bruchpilot-labelled active zones in daily remodelled terminals of Drosophila clock neurons biorxiv.org/cgi/content/sh… #bioRxiv
RewitzLab retweeted
How do animals weigh competing needs to maintain nutrient and fluid balance? Check out our recent review in #BioEssays in which we aim to provide a framework for understanding the polymodal optimization of homeostasis in insects. Also, pretty pictures... onlinelibrary.wiley.com/share/EU9FPTNI…
RewitzLab retweeted
Thanks @crisprflydesign! Nice #CRISPR clones showing that the TNF Receptor wgn plays an important role in lipid metabolism in the #Drosophila intestine. science.org/doi/10.1126/sc…
RewitzLab retweeted
New paper: split-intein Gal4 provides intersectional genetic labeling that is repressible by Gal80. Ewen-Campen, Luan, Xu, Singh, Joshi, Thakkar, Berger, White, Perrimon. PNAS. 2023 doi: 10.1073/pnas.2304730120. Epub 2023 Jun 5. PMID: 37276389
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