Rania Nasis, MD, MBA @ranianasis
The question isn’t who is going to pay for it; it’s why the $#%@ is it so expensive. New York, NY Joined July 2008-
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“In the name of the best within you, do not sacrifice this world to those who are its worst. […] Do not let your fire go out, spark by irreplaceable spark, in the hopeless swamps of the approximate, the not-quite, the not-yet, the not-at-all. Do not let the hero in your soul perish, in lonely frustration for the life you deserved, but have never been able to reach […] The world you desired can be won, it exists, it is real, it is possible, it’s yours.” My favorite quote (in an infamously long speech). Several months of diving into this text only reinforced why it’s stayed with me for so many years. Few passages capture the call to live deliberately, and refuse to settle, quite like this one. It’s a reminder that the world we desire is not something to wait for, but something to build.
TOMORROW.✨️ After weeks of deep text analysis, we’ve finally made it to the final chapter of Ayn Rand's epic. Join @ranianasis to explore the dramatic culmination of the strike, the collapse of the old order, and the enduring philosophical questions left in the wake of "A is
@micsolana not sure what’s worse, their treatment of him, or the fact that in their minds, a “quintessential American” is someone who isn’t good at anything.
@benryanwriter this is probably due to better blood sugar regulation. there’s a link between impaired insulin sensitivity in brain and migraines. even in those that seem to have normal standard metabolic labs.
“why have we left it all to fools?” a haunting question from this week’s reading
NYC is changing, and the warmth of collectivism is officially on the menu. Join host @ranianasis to investigate why Rand’s Looters feel so familiar in 2026. Let's explore what happens when the producers finally say no. interintellect.com/salons/session…
kudos to those like @BradStanfieldMD for actually doing the work in the longevity space. it takes integrity to publish results when they aren’t positive. we have so many unanswered questions around rapamycin and this helps point the way to better future studies.
Our Rapamycin & Exercise clinical trial has just been published! The topline result? Rapamycin didn't help. Instead, it may have made things worse. Here's what we found 🧵 onlinelibrary.wiley.com/doi/epdf/10.10…
an unforgettable party. frenemies circling. implied threats. building against impossible timelines. tension everywhere. triumph and achievement breaking through decay. a glimmer of hope. guilt. shame. pride. an awe-inspiring discovery. a man pushed too far. the world set on fire. and that’s just wrapping up part 1! all building towards a shocking reveal. there’s still room left to join the discussion.
Is need being used as a moral weapon against excellence? Tomorrow in NYC, we dive into the siege on competence. Join @ranianasis to investigate Rearden Metal and whether productivity is a virtue or a liability. Let’s explore the truth behind the slogans.interintellect.com/salons/session…
@anothercohen i got a marketing email from a company pretending to be medvi after that article came out. fraud is everywhere 🤣
@JesseTinsley @BillAckman @X please tell me you did not settle. that’s jus insane.
@JTLonsdale there’s also a cultural rot underpinning this. the haves pretending to care about the have-nots but really just resentful of the have-mores. and increasingly comfortable punishing them for existing. that’s what makes passing regulations in these areas so easy.
@maxlugavere and salad dressings
part of the problem is lack of enforcement. you wouldn’t need so much regulation if fraud was called out and penalties were severe (jail time). but also most of the regulation in place is basically honor system. no one checks unless you really f-ed up or get so big that class action lawyers come looking for pay days.
@josiezayner even if they did somehow work wonders, we don’t have much data on proper dosing and duration. dose makes the poison. not to mention impact of taking multiple peptides with potentially overlapping mechanisms.
i don’t think he fully grasps what a clinical trial (or getting there) really entails. it’s like when you hear newbie biotech founders claim they’re only a couple years away from commercialization when all they have is academic preclinical studies. what agency would approve this to go into humans without longer safety studies in animals first?
@StuartBlitz and they probably spent seven figures on that branding
@PatrickHeizer also, companies already exist that make (in weeks) personalized cancer vaccines for pets. see torigen. torigen.com
it often comes down to people not knowing what they don’t know. there’s a general fear that pharma is bad and keep us from cures to make money. but most people can’t wrap their heads around how insanely complex human biology is and how a fix in one area can cause serious problems in another (maybe immediately, maybe months/years later). and everyone says it’s their body and therefore their choice when things look promising, until outcomes go bad and then it’s the regulators’ fault for not stepping in sooner. and what he did is awesome and love that it’s gotten people so excited about science. and if that inspires more talented people to pursue a career in this field, that’s a win.
not sure the fda can put the cat back in the bag. it’s slow & uneven in enforcement (rarely results in jail) and at times pressured by powerful/loud advocacy groups to look past thin evidence. it’ll be interesting to see if civil courts have an impact here eventually. only a matter of time before someone has a bad side effect and sues rich influence. civil has much lower bar than criminal.
this isn’t about CICO. its mostly about regulatory nuance around calculating calories of novel ingredients. the lawsuit is a money grab — there will be a settlement with lawyers making millions and consumers get a ~$.75 refund. david’s approach to counting calories is generally permissible by fda when ingredients aren’t fully digested, but this is based mostly on company-generated data. so it could draw the attention of the fda to take a closer look. if that happens, i think worst case scenario is that they have to increase calories per g of epg on label but unlikely that it would be as much as fully digested fat. lawyers are exploiting differences between how people think about calories versus how they can be measured. so they can claim consumer harm even if it’s scientifically defensible. bad for brand because this nuance in calorie calculations is something the average consumer doesn’t understand and will lose trust in david as a result. but none of that gets to the bigger question in imo, is epg something we want to be eating in the first place?
Feels like the David lawsuit is effectively a referendum on CICO? Plaintiff: a calorie is a calorie Defendant: the body burns different food types differently
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